Cytogenetics
is a branch of genetics that is concerned with the study of the structure and function of the cell, especially the chromosomes. It includes routine analysis of G-Banded chromosomes, other cytogenetic banding techniques, as well as molecular cytogenetics such asfluorescent in situ hybridization (FISH) and comparative genomic hybridization (CGH).
Cytogenetics is a field under genetics that mainly focuses on the cell, its structure, and how its parts function. It also particularly concentrates on the chromosome and how they are related to several hereditary disorders. Researches and experiments under the field of cytogenetics usually involve defected chromosomes that can tell how disorders and diseases are instigated.
The establishment of how many chromosomes are present in a human led to the emergence of cytogenetics. The discovery that some diseases are consistently indicated by some chromosomal changes was also a great factor in making cytogenetics an important field of research. Since then, many technological and chemical processes have been invented to aid the observation and analysis of chromosomes. Among these processes are the commonly-used comparative genomic hybridization (CGH) and the fluorescence “in situ” hybridization (FISH).
Both CGH and FISH often involve laboratory work, so cytogeneticists are technicians and scientists who are usually “behind the limelight,” so to speak, making sure that doctors get the correct information about a certain disease.
Role of Cytogenetics
is a branch of genetics that is concerned with the study of the structure and function of the cell, especially the chromosomes. It includes routine analysis of G-Banded chromosomes, other cytogenetic banding techniques, as well as molecular cytogenetics such asfluorescent in situ hybridization (FISH) and comparative genomic hybridization (CGH).
Cytogenetics is a field under genetics that mainly focuses on the cell, its structure, and how its parts function. It also particularly concentrates on the chromosome and how they are related to several hereditary disorders. Researches and experiments under the field of cytogenetics usually involve defected chromosomes that can tell how disorders and diseases are instigated.
The establishment of how many chromosomes are present in a human led to the emergence of cytogenetics. The discovery that some diseases are consistently indicated by some chromosomal changes was also a great factor in making cytogenetics an important field of research. Since then, many technological and chemical processes have been invented to aid the observation and analysis of chromosomes. Among these processes are the commonly-used comparative genomic hybridization (CGH) and the fluorescence “in situ” hybridization (FISH).
Both CGH and FISH often involve laboratory work, so cytogeneticists are technicians and scientists who are usually “behind the limelight,” so to speak, making sure that doctors get the correct information about a certain disease.
- FISH is a technique that makes chromosomes light up using fluorescent molecules in order to specify any anomalies in the chromosome arrangement. These anomalies would usually show up in a different color than those of normal chromosomes.
- CGH, on the other hand, is a method that can spot any disturbing changes in the chromosomes, such as in samples from malignant cysts. In both methods, samples are often observed under the microscope, since chromosomes are very minute.
Role of Cytogenetics
- Cytogenetics plays a significant role in the medical field, as laboratory results help doctors diagnose a disease and decide on the best treatment for the patient.
- This field is especially helpful for hereditary and congenital disorders such as mental retardation, Down syndrome and Edward’s syndrome.
- Cancer and infertility can also get better diagnosis and treatment.
- Cytogenetics has also been a vital factor in preventing people from getting cancer by looking at gene predictors that indicate the chances of obtaining cancer.
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